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Close Thanks for visiting. By Ronnie Cohen , Reuters Health. NEW YORK Reuters Health - People who take antidepressants tend to put on a few pounds, a new study confirms, and some of the drugs are linked to more weight gain than others. Using health records from one New England healthcare system, researchers studied 19, adults treated with antidepressants, recording their weights over the course of a year.
The results showed that people taking citalopram Celexa , from a class of antidepressants known as selective serotonin reuptake inhibitors, or SSRIs, gained more than two and a half pounds, on average.
Other SSRIs were associated with weight gain similar to citalopram, with people taking fluoxetine Prozac gaining on average a pound and a half and those taking sertraline Zoloft gaining nearly two pounds, the authors write in JAMA Psychiatry. On the other hand, people taking bupropion Wellbutrin lost on average nearly half a pound. The tricyclic antidepressants nortriptyline and amitriptyline were also linked with significantly less weight gain than the SSRIs.
Products and services. Can antidepressants cause weight gain? Answer From Daniel K. With Daniel K. Thank you for Subscribing Our Housecall e-newsletter will keep you up-to-date on the latest health information. Please try again. Something went wrong on our side, please try again. Show references Gafoor R, et al. Antidepressant utilisation and incidence of weight gain during 10 years' follow-up: Population based cohort study.
Hirsch M, et al. Selective serotonin reuptake inhibitors: Pharmacology, administration, and side effects. Accessed Oct. Simon G. Unipolar major depression in adults: Choosing initial treatment. Preventing weight gain. Centers for Disease Control and Prevention.
Lee SH, et al. Is increased antidepressant exposure a contributory factor to the obesity pandemic? Translational Psychiatry. Carvalho AF, et al. The safety, tolerability and risks associated with the use of newer generation antidepressant drugs: A critical review of the literature. Psychotherapy and Psychosomatics. Arterburn D, et al. Long-term weight change after initiating second-generation antidepressants.
Journal of Clinical Medicine. Tarleton EK, et al. Primer for nutritionists: Managing the side effects of antidepressants. Himmerich H, et al. Weight gain and metabolic changes during treatment with antipsychotics and antidepressants. Krieger CA expert opinion. Mayo Clinic, Rochester, Minn.
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